● 2015年代表性论文
2015年药学院在聚焦重大前沿科学问题、引领科学发展方面取得了系统性原创成果,在药学相关领域公认的重要期刊上发表了200余篇高水平学术论文。一系列重要科研成果发表于J. Med. Chem., Eur. J .Med. Chem., J. Nat. Prod., J. Am. Chem. Soc., Angew. Chem. Int. Biomaterials等高水平专业期刊。
本年度全院共发表论文392篇(SCI收录267篇),会议报告论文127 篇。
1、国内论文140篇,核心期刊收录128篇,SCI收录7篇。
2、国外论文252篇,SCI收录250。其中第一完成单位为我院发表的论文205篇,研究文章204篇,综述4篇。
1)影响因子最高的研究型文章为焦宁教授课题组在JOURNAL OF THE AMERICAN CHEMICAL SOCIETY.杂志上发表的2篇文章Mn-Catalyzed Highly Efficient Aerobic Oxidative Hydroxyazidation of Olefins: A Direct Approach to beta-Azido Alcohols和Rh-Catalyzed Construction of Quinolin-2(1H)-ones via C-H Bond Activation of Simple Anilines with CO and Alkynes,影响因子12.11;王克威课题组还在Nature Communications杂志上发表了1篇文章A Pain-Inducing Centipede Toxin Targets the Heat Activation Machinery of Nociceptor TRPV1,影响因子11.47。
2)国外SCI收录(第一完成单位全部为我院)文章中影响因子11.0~12.1有6篇;7.0~10.0有15篇;4.0~7.0有51篇。
● 2015年影响因子5以上的文章目录
序号 |
论文题目 |
杂志名称 |
作 者 |
SCI影响因子 |
1 |
Mn-Catalyzed Highly Efficient Aerobic Oxidative Hydroxyazidation of Olefins: A Direct Approach to beta-Azido Alcohols |
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY |
Sun, Xiang; Li, Xinyao; Song, Song; Zhu, Yuchao; Liang, Yu-Feng; Jiao, Ning |
12.113 |
2 |
Rh-Catalyzed Construction of Quinolin-2(1H)-ones via C-H Bond Activation of Simple Anilines with CO and Alkynes |
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY |
Li, Xinyao; Li, Xinwei; Jiao, Ning |
12.113 |
3 |
A Pain-Inducing Centipede Toxin Targets the Heat Activation Machinery of Nociceptor TRPV1 |
Nature Communications |
Shilong Yang, Fan Yang, Ningning We, Jing Hong, Bowen Li, Lei Luo, Mingqiang Rong, Vladimir Yarov-Yarovoy, Jie Zheng, KeWei Wang, Ren Lai |
11.47 |
4 |
Splitting a Substrate into Three Parts: Gold-Catalyzed Nitrogenation of |
Angew. Chem. Int. Ed. |
Chong Qin, Yijin Su, Tao Shen, Xiaodong Shi, and Ning Jiao |
11.261 |
5 |
Catalytic Asymmetric Total Synthesis of (-)-Galanthamine and (-)-Lycoramine |
Angew. Chem. Int. Ed. |
Lei Li, Qiao Yang, Yuan Wang, Yanxing Jia |
11.261 |
6 |
Protecting-Group-Free Enantioselective Synthesis of (-)-Pallavicinin and (+)-Neopallavicinin |
Angew. Chem. Int. Ed. |
Bin Huang, Lei Guo, Yanxing Jia |
11.261 |
7 |
Aerobic Oxidation of Pd-II to Pd-IV by Active Radical Reactants: Direct C-H Nitration and Acylation of Arenes via Oxygenation Process with Molecular Oxygen |
ACS CATALYSIS |
Liang, Yu-Feng; Li, Xinyao; Wang, Xiaoyang; Yan, Yuepeng; Feng, Peng; Jiao, Ning |
9.312 |
8 |
Ligand-Promoted Pd-Catalyzed Oxime Ether Directed C-H Hydroxylation of Arenes |
ACS CATALYSIS |
Liang, Yu-Feng; Wang, Xiaoyang; Yuan, Yizhi; Liang, Yujie; Li, Xinyao; Jiao, Ning |
9.312 |
9 |
Copper-catalyzed direct transformation of simple alkynes to alkenyl nitriles via aerobic oxidative N-incorporation |
CHEMICAL SCIENCE |
Huang, Xiaoqiang; Lia, Xinyao; Jiao, Ning |
9.211 |
10 |
Broaden the versatility of lentiviral vector as a tool in nucleic acid research via genetic code expansion |
Nucleic Acids Res |
Zheng, Yongxiang; Yu, Fei; Wu, Yiming; Si, Longlong; Xu, Huan; Zhang, Chuanling; Xia, Qing; Xiao, Sulong; Wang, Qi; He, Qiuchen; Chen, Peng; Wang, Jiangyun; Zhang, Li He; Taira, Kazunari; Zhou, Demin |
9.112 |
11 |
The use of a-conotoxin ImI to actualize the targeted delivery of paclitaxel micelles to a7 nAChR-overexpressing breast cancer |
Biomaterials |
Dong Mei, Zhiqiang Lin, Jijun Fu, Bing He, Wei Gao, Ling Ma, Wenbing Dai, Hua Zhang,Xueqing Wang, Jiancheng Wang, Xuan Zhang, Wanliang Lu, Demin Zhou, Qiang Zhang |
8.557 |
12 |
Tumor-specific penetrating peptides-functionalized hyaluronic acid-d-α-tocopheryl succinate based nanoparticles for multi-task delivery to invasive cancers |
Biomaterials |
De-Sheng Liang, Hai-Tao Su, Yu-Jie Liu, Ai-Ting Wang, Xian-Rong Qi* |
8.557 |
13 |
Roles of ligand and TPGS of micelles in regulating internalization, penetration and accumulation against sensitive or resistant tumor and therapy for multidrug resistant tumors |
Biomaterials |
Ai-ting Wang, De-sheng Liang, Yu-jie Liu, Xian-rong Qi* |
8.557 |
14 |
Efficient bromination of olefins, alkynes, and ketones with dimethyl sulfoxide and hydrobromic acid |
GREEN CHEMISTRY |
Song, Song; Li, Xinwei; Sun, Xiang; Yuan, Yizhi; Jiao, Ning |
8.02 |
15 |
From simple organobromides or olefins to highly value-added bromohydrins: a versatile performance of dimethyl sulfoxide |
GREEN CHEMISTRY |
Song, Song; Huang, Xiaoqiang; Liang, Yu-Feng; Tang, Conghui; Li, Xinwei; Jiao, Ning |
8.02 |
16 |
Macrophage mediated biomimetic delivery system for the treatment of lung metastasis of breast cancer |
Journal of Controlled Release |
Jijun Fu , Dan Wang, Dong Mei, Haoran Zhang, Zhaoyang Wang, Bing He, Wenbing Dai, Hua Zhang,Xueqing Wang, Qiang Zhang |
7.705 |
17 |
A novel localized co-delivery system with lapatinib microparticles and paclitaxel nanoparticles in a peritumorally injectable in situ hydrogel |
Journal of Controlled Release |
Hongxiang Hu,Zhiqiang Lin,Bing He,Wenbing Dai,Xueqing Wang,Jiancheng Wang , Xuan Zhang,Hua Zhang*, Qiang Zhang** |
7.705 |
18 |
The permeability and transport mechanism of graphene quantum dots (GQDs) across the biological barrier |
Nanoscale |
Xin-yi Wang, Rong Lei, Hong-duang Huang, Na Wanga, Lan Yuan, Ru-yue Xiaoa, Li-dan Baia, Xue Lia, Li-mei Lid and Xiao-da Yang |
7.394 |
19 |
A comparative study of thermo-sensitive hydrogels with water-insoluble paclitaxel in molecule, nanocrystal and microcrystal dispersions |
Nanoscale |
Zhiqiang Lin,Dong Mei,Meiwan Chen,Yitao Wang,Xianhui Chen,Zhaoyang Wang,Bing He,Hua Zhang,Xueqing Wang,Wenbing Dai*,Yuxin Yin*,and Qiang Zhang* |
7.394 |
20 |
Effects of PEGylated paclitaxel nanocrystals on breast cancer and its lung metastasis |
Nanoscale |
Hua Zhang, Hongxiang Hu, Haoran Zhang, Wenbing Dai, Xinglin Wang,Xueqing Wang* and Qiang Zhang* |
7.394 |
21 |
PSMA-mediated endosome escape-accelerating polymeric micelles for targeted therapy of prostate cancer and the real time tracing of their intracellular trafficking |
Nanoscale |
Yajie Gao, Yanfang Li, Yushu Li, Lan Yuan, Yanxia Zhou, Jinwen Li, Lei Zhao, Chao Zhang, Xinru Li and Yan Liu |
7.394 |
22 |
Supramolecular assemblies of novel aminonucleoside phospholipids and their bonding to nucleic acids |
Chem. Comm. |
Delin Pan, Jing Sun, Hongwei Jin, Yating Li, Liyu Li, Yun Wu, Lihe Zhang, Zhenjun Yang* |
6.834 |
23 |
Concise Synthesis of the Tricyclic Skeleton of Crotobarin and Crotogoudin via a Gold-catalyzed Cycloisomerization Reaction |
Chem. Commun. |
Yinliang Guo, Qiang Liu, Yanxing Jia |
6.834 |
24 |
Photoinduced C–S Bond Cleavage of Thioglycosides and Glycosylation |
Organic letters |
Run-Ze Mao,Fan Guo, De-Cai Xiong,Qin Li, Jinyou Duan,Xin-Shan Ye |
6.364 |
25 |
Direct C-H Trifluoromethylation of Glycals by Photoredox Catalysis |
Organic letters |
Bang Wang,De-Cai Xiong,and Xin-Shan Ye |
6.364 |
26 |
Cu-Catalyzed Concise Synthesis of Pyridines and 2-(1H)-Pyridones from Acetaldehydes and Simple Nitrogen Donors |
ORGANIC LETTERS |
Li, Ziyuan; Huang, Xiaoqiang; Chen, Feng; Zhang, Chun; Wang, Xiaoyang; Jiao, Ning |
6.364 |
27 |
I-2- or NBS-Catalyzed Highly Efficient alpha-Hydroxylation of Ketones with Dimethyl Sulfoxide |
ORGANIC LETTERS |
Liang, Yu-Feng; Wu, Kai; Song, Song; Li, Xinyao; Huang, Xiaoqiang; Jiao, Ning |
6.364 |
28 |
Efficient and Practical Oxidative Bromination and Iodination of Arenes and Heteroarenes with DMSO and Hydrogen Halide: A Mild Protocol for Late-Stage Functionalization |
ORGANIC LETTERS |
Song, Song; Sun, Xiang; Li, Xinwei; Yuan, Yizhi; Jiao, Ning |
6.364 |
29 |
Metal-Free Nitrogenation of 2-Acetylbiphenyls: Expeditious Synthesis of Phenanthridines |
ORGANIC LETTERS |
Tang, Conghui; Yuan, Yizhi; Jiao, Ning |
6.364 |
30 |
Silver-Catalyzed Decarboxylative Azidation of Aliphatic Carboxylic Acids |
ORGANIC LETTERS |
Zhu, Yuchao; Li, Xinyao; Wang, Xiaoyang; Huang, Xiaoqiang; Shen, Tao; Zhang, Yiqun; Sun, Xiang; Zou, Miancheng; Song, Song; Jiao, Ning |
6.364 |
31 |
Microbacterins A and B, New Peptaibols from the Deep Sea Actinomycete Microbacterium sediminis sp. nov. YLB-01(T) |
Organic Letters |
Liu, Dong; Lin, Hong; Proksch, Peter; Tang, Xixiang; Shao, Zhongze; Lin, Wenhan |
6.364 |
32 |
Asymmetric Total Synthesis of (+)–Dragmacidin D Reveals Unexpected Stereo Complexity |
Org. Lett. |
Fengying Zhang, Bin Wang, Pritesh Prasad, Robert J. Capon, Yanxing Jia |
6.364 |
33 |
Exotines A and B, two Heterodimers of isopentenyl-substitutedindole and coumarinderivatives from Murraya exotica. |
Org. Lett. |
Bing-Yu Liu, Chen Zhang, Ke-Wu Zeng, Jun Li, Xiao-Yu Guo, Ming-Bo Zhao, Peng-FeiTu,and Yong Jiang*. |
6.364 |
34 |
Traditional Chinese patent medicines for cancer treatment in China: a nationwide medical insurance data analysis |
Oncotarget |
Wu M, Lu P, Shi L, Li S. |
6.359 |
35 |
A nanostructure of functional targeting epirubicin liposomes dually modified with aminophenyl glucose and cyclic pentapeptide used for brain glioblastoma treatment. |
Oncotarget |
Cheng-Xiang Zhang, Wei-Yu Zhao, Lei Liu, Rui-Jun Ju, Li-Min Mu, Yao Zhao, Fan Zeng, Hong-Jun Xie, Yan Yan, Wan-Liang Lu |
6.359 |
36 |
Application of functional vincristine plus dasatinib liposomes to deletion of vasculogenic mimicry channels in triple-negative breast cancer |
Oncotarget |
Fan Zeng, Rui-Jun Ju, Lei Liu, Hong-Jun Xie, Li-Min Mu, Yao Zhao, Yan Yan, Ying-Jie Hu, Jia-Shuan Wu, Wan-Liang Lu |
6.359 |
37 |
Development of next generation of therapeutic IFN-alpha2b via genetic code expansion |
Acta Biomaterialia |
Bo Zhang, Huan Xu, Jingxian Chen, Yongxiang Zheng, Yiming Wu, Longlong Si, Ling Wu, Chuanling Zhang, Gang Xia, Lihe Zhang, Demin Zhou |
6.025 |
38 |
pH-responsive polymeric micelles based on poly(2-ethyl-2-oxazoline)-poly(D,L-lactide) for tumor-targeting and controlled delivery of doxorubicin and P-gp inhibitor |
Acta Biomaterialia |
Yong Zhao, Yanxia Zhou, Dishi Wang, Yajie Gao, Jinwen Li, Shujin Ma, Lei Zhao, Chao Zhang, Yan Liu and Xinru Li |
6.025 |
39 |
Enhanced antitumor efficacy by cyclic RGDyK-conjugated and paclitaxel-loaded pH-responsive polymeric micelles |
Acta Biomaterialia |
Yajie Gao, Yanxia Zhou, Lei Zhao, Chao Zhang, Yushu Li, Jinwen Li, Xinru Li and Yan Liu |
6.025 |
40 |
Targeting and microenvironment responsive lipid nanocarrier for the enhancement of Targeting and Microenvironment-Responsive Lipid Nanocarrier for the Enhancement of Tumor Cell Recognition and Therapeutic Efficiency |
Adv. Healthcare Mater. |
Wei Gao , Tingting Meng , Nianqiu Shi , Hongmeng Zhuang , Zhenzhen Yang , Xianrong Qi* |
5.797 |
41 |
Novel mechanisms for superoxide-scavenging activity of human manganese superoxide dismutase determined by the K68 key acetylation site. |
Free Radic Biol Med |
Lu J, Cheng K, Zhang B, Xu H, Cao Y, Guo F, Feng X, Xia Q*. |
5.736 |
42 |
Bioorthogonal SERS Nanoprobes for Mulitplex Spectroscopic Detection and Tumor Cell Targeting and Tissue Imaging |
Chem. Eur. J |
Junzhou Wu, Duanwei Liang, Qingqing Jin, Jie Liu, Meiling Zheng Xuanming Duan, and Xinjing Tang |
5.731 |
43 |
Cationic Cobalt(III)-Catalyzed Aryl and Alkenyl C-H Amidation: A Mild Protocol for the Modification of Purine Derivatives. |
Chemistry (Weinheim an der Bergstrasse, Germany) |
Liang, Yujie; Liang, Yu-Feng; Tang, Conghui; Yuan, Yizhi; Jiao, Ning |
5.731 |
44 |
Biocatalysis of cycloastragenol by Syncephalastrum racemosum and Alternaria alternata to discover anti-aging derivatives. |
Adv. Synth. Catal. |
Lin-min Feng, Shuai Ji, Xue Qiao, Zi-wei Li, Xiong-hao Lin, Min Ye*. |
5.663 |
45 |
Visualizing Fluoride ion in Mitochondria and Lysosome of Living Cells and in Living Mice with Positively Charged Ratiometric Probes |
Anal. Chem |
Zhisheng Wu, Xinjing Tang |
5.636 |
46 |
Therapeutic potential of targeted multifunctional nanocomplex co-delivery of siRNA and low-dose doxorubicin in breast cancer |
Cancer Letters |
Dawen Dong,Wei Gao, Yujie Liu, Xian-Rong Qi* |
5.621 |
47 |
Systemic Administration of siRNA via cRGD-containing Peptide |
Scientific Reports |
Huang Y, Wang X, Huang W, Cheng Q, Zheng S, Guo S, Cao H, Liang XJ, Du Q, Liang Z |
5.597 |
48 |
Photouncaged Sequence-specific Interstrand DNA Cross-Linking with Photolabile 4-oxo-enalmodified Oligonucleotides |
Sci. Rep. |
Jingjing Sun, Xinjing Tang |
5.578 |
49 |
Natural small molecule FMHM |
Scientific Reports |
Ke-Wu Zeng1, Li-Xi Liao1, Hai-Ning Lv1, Fang-Jiao Song2, Qian Yu2, Xin Dong1, Jun Li3, |
5.578 |
50 |
Neuroprotective Effects of a standardized flavonoid extract of safflower against Neurotoxin-Induced Cellular and Animal Models of Parkinson's Disease |
Scientific Reports |
Rutong Ren, Chunyan Shi, Jing Cao, Yi Sun, Xin Zhao, Chen Wang, Yongfei Guo, Hui Lei, Hanjie Jiang, Nuramatjan Ablata, , Jiamin Xu, Wan Li, Yingcong Ma, Xianrong Qi, Min Ye, Xiaoping Pu*, Hongbin Han, * |
5.578 |
51 |
Cyclic Adenosine 5 '-Diphosphoribose (cADPR) Mimics Used as Molecular Probes in Cell Signaling |
CHEMICAL RECORD |
Zhang, Liangren; Yue, Jianbo; Zhang, Li-He |
5.492 |
52 |
Discovery of Pentacyclic Triterpenoids as Potential Entry Inhibitors of Influenza Viruses. |
J. Med. Chem. |
Maorong Yu, Longlong Si, Yufei Wang, Yiming Wu, Fei Yu, Pingxuan Jiao, Yongying Shi, Han Wang, Sulong Xiao, Ge Fu, Ke Tian, Yitao Wang, Zhihong Guo, Xinshan Ye, Lihe Zhang |
5.48 |
53 |
Highly Substituted Cyclopentane?CMP Conjugates as Potent Sialyltransferase Inhibitors |
Journal of Medicinal Chemistry |
Wenming Li,Youhong Niu, De-Cai Xiong,Xiaoping Cao,nd Xin-Shan Ye |
5.447 |
54 |
A Combination of Targeted Sunitinib Liposomes and Targeted Vinorelbine Liposomes for Treating Invasive Breast Cancer |
Journal of Biomedical Nanotechnology |
Ji-Feng Shi, Meng-Ge Sun, Xiu-Ying Li, Yao Zhao, Rui-Jun Ju, Li-Min Mu, Yan Yan, Xue-Tao Li, Fan Zeng, and Wan-Liang Lu |
5.338 |
55 |
Structure-guided creation of AcAP5-derived and platelet targeted factor Xa inhibitors |
Biochem Pharmacol |
Zhu Y, Lin Y, Liu A, Shui M, Li R, Liu X, Hu W, Wang Y |
5.009 |
56 |
Dopamine enhances the response of sunitinib in the treatment of drug-resistant breast cancer: involvement of eradicating cancer stem-like cells |
Biochemical Pharmacology |
Wang, Siyuan; Mou, Zhenzhen; Ma, Yuanheng; Li, Jian; Li, Jingyun; Ji, Xiwei; Wu, Kehua; Li, Liang; Lu, Wei; Zhou, Tianyan* |
5.009 |