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2013年

 ●  2013年代表性论文    

我院教师为责任作者的多篇论文分别获得中国药学会、北京药学年会、《药学学报》优秀论文奖;北京大学“优秀博士论文”奖;ACP lectureship award (日本、香港);Tieme Chemistry Journal Award。

一系列重要科研成果发表于Angew. Chem. Int. Ed., J. Am. Chem. Soc., Nucleic Acids Res.,  Biomaterials等高水平专业期刊。

本年度全院共发表论文350篇(SCI收录252篇),会议报告论文83 篇。

1、国内论文110篇,全部为核心期刊收录,SCI收录12篇。

2、国外论文240篇,全部为SCI收录。其中第一完成单位为我院发表的论文207篇,研究文章204篇,综述3篇。

1)影响因子最高的研究型文章为贾彦兴教授课题组和焦宁教授课题组在Angew. Chem. Int. Ed. 杂志上分别发表的1篇和4篇文章,影响因子为13.734。

2)国外SCI收录(第一完成单位全部为我院)文章中影响因子>13.0有5篇;10.0~13.0有3篇;8.0~10.0有3篇;7.0~8.0有14篇;6.0~7.0有11篇;5.0~6.0有9篇;4.0~5.0有23篇;3.0~4.0有30篇;1.0~3.0有96篇。

 ●  2013年影响因子5以上的文章目录        


序号

论文题目

杂志名称

 

SCI影响因子

1

Intramolecular Larock Indole Synthesis for the Preparation of 3,4-Fused Tricyclic Indoles and Its Application in the Total Synthesis of Fargesine

Angew. Chem. Int. Ed.

Dong Shan, Yan Gao, Yanxing Jia*

13.734

2

Highly Selective Csp2-Csp Bond Cleavage: The Nitrogenation of Alkynes to Amides

Angew. Chem. Int. Ed.

Chong Qin, Peng Feng, Yang Ou, Tao Shen, Teng Wang and Ning Jiao

13.734

3

Ag-catalyzed Nitrogenation of Alkynes: A Direct Approach to Nitriles via C-C Triple Bond Cleavage,

Angew. Chem. Int. Ed.

Tao Shen, Teng Wang, Chong Qin, and Ning Jiao

13.734

4

Catalyst-controlled Highly Selective Coupling and Oxygenation of Olefins: A Direct Approach to Alcohols, Ketones and Diketones

Angew. Chem. Int. Ed.

Yijin Su, Xiang Sun, Guolin Wu, and Ning Jiao

13.734

5

PdCl2 and NHPI Cocatalyzed Csp2-H Hydroxylation via Dioxygen Activation

Angew. Chem. Int. Ed.

Yuepeng Yan, Peng Feng, Qing-Zhong Zheng, Yu-Feng Liang, Jingfen Lu, and Ning Jiao

13.734

6

TEMPO-catalyzed Aerobic Oxygenation and Nitrogenation of Olefins via C═C Double-Bond Cleavage

Journal of the American Chemical Society

Teng WangNing Jiao

10.677

7

Cu-Catalyzed Esterification Reaction via Aerobic Oxygenation and C-C Bond Cleavage: An Approach to α-Ketoesters, J. Am. Chem. Soc.

Journal of the American Chemical Society

Chun Zhang, Ning Jiao

10.677

8

Copper-catalyzed C-H Azidation of Anilines under Mild Conditions

Journal of the American Chemical Society

Conghui Tang and Ning Jiao

10.677

9

Nanotoxicity comparison of four amphiphilic polymeric micelles with similar hydrophilic or hydrophobic structure

Particle and Fibre Toxicology

Bo Zhao, Xue-Qing Wang, Xiao-You Wang, Hua Zhang, Wen-Bing Dai, Jun Wang, Zhen-Lin Zhong, Hou-Nan Wu and Qiang Zhang

9.178

10

Caged Circular Antisense Oligonucleotides for Photomodulation of RNA Digestion and Gene Expression in Cells

Nucleic Acids Research

Li Wu, Yuan Wang, Junzhou Wu, Jie Wang, Xinjing Tang

8.278

11

CovalentDock Cloud: a web server for automated covalent docking.

Nucleic Acids Research

Xuchang Ouyang1,2, Shuo Zhou1, Zemei Ge1, Runtao Li1,* and Chee Keong Kwoh2,*

8.278

12

The transport mechanisms of polymer nanoparticles in Caco-2 epithelial cells

Biomaterials

Bing He, Ping Lin, Zengrong Jia, Wenwen Du, Wei Qu, Lan Yuan, Wenbing Dai, Hua Zhang,Xueqing Wang, Jiancheng Wang, Xuan Zhang, Qiang Zhang*

7.604

13

The transport pathways of polymer nanoparticles in MDCK epithelial cells

Biomaterials

Bing He, Zengrong Jia, Wenwen Du, Chao Yu, Yuchen Fan, Wenbing Dai, Lan Yuan,Hua Zhang, Xueqing Wang, Jiancheng Wang, Xuan Zhang, Qiang Zhang*

7.604

14

The reduction of tumor interstitial fluid pressure by liposomal imatinib and its effect on combination therapy with liposomal doxorubicin

Biomaterials

Yuchen Fan, Wenwen Du, Bing He, Fengying Fu, Lan Yuan, Hounan Wu, Wenbing Dai, Hua Zhang , Xueqing Wang, Jiancheng Wang, Xuan Zhang, Qiang Zhang

7.604

15

A specific peptide ligand-modified lipid nanoparticle carrier for the inhibition of tumor metastasis growth

Biomaterials

Zhaohui Wang, Yang Yu, Wenbing Dai, Jingrong Cui, Hounan Wu, Lan Yuan, Hua Zhang, Xueqing Wang, Jiancheng Wang, Xuan Zhang, Qiang Zhang

7.604

16

Transferrin receptor specific nanocarriers conjugated with functional 7peptide for oral drug delivery

Biomaterials

Wenwen Du, Yuchen Fan, Nan Zheng, Bing He, Lan Yuan, Hua Zhang, Xueqing Wang, Jiancheng Wang, Xuan Zhang, Qiang Zhang

7.604

17

The effect of hydrophilic and hydrophobic structure of amphiphilic polymeric micelles on their transport in epithelial MDCK cell

Biomaterials

Chao Yu, Bing He, Meng-Hua Xiong, Hua Zhang, Lan Yuan, Ling Ma, Wen-Bing Dai, Jun Wang, Xing-Lin Wang, Xue-Qing Wang*, Qiang Zhang*

7.604

18

Modulation of drug-resistant membrane and apoptosis proteins of breast cancer stem cells by targeting berberine liposomes

Biomaterials.

Ma X, Zhou J, Zhang CX, Li XY, Li N, Ju RJ, Shi JF, Sun MG, Zhao WY, Mu LM, Yan Y, Lu WL*.

7.604

19

The anticancer efficacy of paclitaxel liposomes modified with mitochondrial targeting conjugate in resistant lung cancer

Biomaterials.

Zhou J, Zhao WY, Ma X, Ju RJ, Li XY, Li N, Sun MG, Shi JF, Zhang CX, Lu WL*

7.604

20

Development of targeting lonidamine liposomes that circumvent drug-resistant cancer by acting on mitochondrial signaling pathways.

Biomaterials.

Li N, Zhang CX, Wang XX, Zhang L, Ma X, Zhou J, Ju RJ, Li XY, Zhao WY, Lu WL*

7.604

21

PSA-responsive and PSMA-mediated multifunctional liposomes for targeted therapy of prostate cancer

Biomaterials

Xiang Bai, Dong Dawen, Shi Nianqiu, Gao Wei, Yang Zhenzhen, Cui Yi, Cao Deying, Qi Xianrong Qi

7.604

22

pH-responsive complexes using prefunctionalized polymers for synchronous delivery of doxorubicin and siRNA to cancer cells

Biomaterials

Dong Dawen, Xiang Bai,Gao Wei, Yang Zhenzhen, Li Jingquan Li, Qi Xianrong

7.604

23

Chemotherapeutic drug delivery to cancer cells using a combination of folate targeting and tumor microenvironment-sensitive polypeptides

Biomaterials

Gao Wei, Xiang Bai, Meng Tingting, Liu Feng, Qi Xianrong

7.604

24

Anti-tumor and anti-angiogenic effect of metronomic cyclic NGR-modified liposomes containing paclitaxel.

Biomaterials.

Luo LM, Huang Y, Zhao BX, Zhao X, Duan Y, Du R, Yu KF, Song P, Zhao Y, Zhang X*, Zhang Q.

7.604

25

Self-assembly cationic nanoparticles based on cholesterol-grafted bioreducible poly(amidoamine) for siRNA delivery.

Biomaterials

Cheng-Jun Chen, Jian-Cheng Wang*, En-Yu Zhao, Ling-Yan Gao, Qiang Feng, Xiao-Yan Liu, Zhi-Xia Zhao, Xiao-Fei Ma, Wen-Jie Hou, Liang-Ren Zhang, Wan-Liang Lu, Qiang Zhang

7.604

26

Catalyst Free Approach to Benzimidazoles Using Air as the Oxidant at Room Temperature

Green Chem.

Chun Zhang, Liangren Zhang and Ning Jiao

6.828

27

Ru(II)-Catalyzed Intermolecular C-H Amidation of Weakly Coordinating Ketones

Chem. Commun

Qing-Zhong Zheng, Yu-Feng Liang, Chong Qin, and Ning Jiao

6.378

28

Recyclable Copper Catalyzed Nitrogenation of Biphenyl Halides: A Direct Approach to Carbazoles

Chem. Commun

Yang Ou, and Ning Jiao

6.378

29

Copper-Catalyzed Direct Oxidative Annulation of N-Iminopyridinium Ylides with Terminal Alkynes Using O2 as Oxidant

Chem. Commun.

Shengtao Ding, Yuepeng, Yan, and Ning Jiao

6.378

30

An efficient organocatalytic enantioselective Michael addition of aryl methyl ketones with 2-furanones: highly functionalized chiral 3,4-substituted lactones

Chem. Commun.

Wang, Wei; Wang, Junfeng; Zhou, Shuo; Sun, Qi; Ge, Zemei; Wang, Xin; Li, Runtao

6.378

31

Single modification at position 14 of siRNA strand abolishes its gene-silencing activity by decreasing both RISC loading and target degradation.

FASEB J.

Zheng J, Zhang L, Zhang J, Wang X, Ye K, Xi Z, Du Q, Liang Z.

6.222

32

Nitrosporeusines A and B, Unprecedented Thioester-Bearing Alkaloids from the Arctic Streptomyces nitrosporeus

Org. Lett.

Aigang Yang, Longlong Si, Zhenping Shi, Li Tian*, Dong Liu, Demin Zhou, Peter Proksch, and Wenhan Lin"

6.142

33

Total Synthesis of Rugulovasine A

Org. Lett.

Yu-An Zhang, Qiang liu, Chao Wang, Yanxing Jia*

6.142

34

Direct Olefination at the C-4 Position of Tryptophan via C-H Activation: Application to Biomimetic Synthesis of Clavicipitic Acid

Org. Lett.

Qiang liu, Qingjiang Li, Yongfan Ma, Yanxing Jia*

6.142

35

Pd-Catalyzed Tandem C–H Azidation and N–N Bond Formation of Arylpyridines: A Direct Approach to Pyrido[1,2-b]indazoles

Org. Lett.

Qing-Zhong Zheng, Peng Feng, Yu-Feng Liang, Ning Jiao

6.142

36

Relay Catalysis by a Multifunctional Cu Catalyst in a Tandem Dehydro-/Dehalogenation Sequence along with N-Arylation

Org. Lett.

Lei Liang; Wei Wang; Fengrong Xu; Yan Niu; Qi Sun; *Ping Xu

6.142

37

Total Synthesis of (+)- and (-)-Decursivine and (±)-Serotobenine via a Cascade Witkop Photocyclization/Elimination/Addition Sequence: Scope and Mechanistic Insights

Chem. Eur. J.

Weimin Hu, Hua Qin, Yuxin Cui, Yanxing Jia*

5.831

38

Direct Transformation of Methyl Imines to α-Iminonitriles under Mild and Transition-Metal Free Condition

Chem. Eur. J.

Feng Chen, Xiaoqiang Huang, Yuxin Cui, and Ning Jiao

5.831

39

Rational Design, Green Synthesis, and Initial Evaluation of a Series of Full-Color Tunable Fluorescent Dyes Enabled by the Copper-Catalyzed N-Arylation of 6-Phenyl Pyridazinones and Their Application in Cell Imaging

Chemistry-A European Journal

Lei Liang; Wei Wang; Jun Wu; Fengrong Xu; Yan Niu; *Bo Xu; *Ping Xu

5.831

40

Development of oleanane-type triterpenes as a new class of HCV entry inhibitors

J. Med. Chem.

Fei Yu,, Qi Wang, Zhen Zhang, Yiyun Peng, Kunbo Chen, Chuanke Zhao,Chuanling Zhang, Maorong Yu, Dian Sun, Lihe Zhang, and Demin Zhou

5.614

41

Novel Pyridinone Derivatives As Non-Nucleoside Reverse Transcriptase Inhibitors (NNRTIs) with High Potency against NNRTIResistant HIV-1 Strains,

J. Med. Chem.

Amin Li, Yabo Ouyang, Ziyun Wang, Yuanyuan Cao, Xiangyi Liu, Li Ran, Chao Li, Li Li, Liang Zhang, Kang Qiao, Weisi Xu, Yang Huang, Zhili Zhang, Chao Tian, Zhenming Liu, Shibo Jiang, Yiming Shao, Yansheng Du, Liying Ma,* Xiaowei Wang,* Junyi Liu*,

5.614

42

Copper-catalyzed Oxidative Transformation of Aryl Propargylic Azides to Aryl Propiolonitriles

Adv. Synth. Cat.

Teng Wang, Hang Yin, and Ning Jiao

5.535

43

Highly Efficient and Diastereoselective Povarov-like Reaction Involving O-pivaloylated D-galactosylimine

Adv. Synth. Cat.

Gang Wang, Boyu Li, Qinghua Lou, Zhong-Jun Li, Xiang-Bao Meng,

5.535

44

A Copper-Catalyzed Aerobic Cascade Dehydrogenative Dehalogenative Reaction

Adv. Synth. Cat.

Liang Lei; Yang Guanyu; Wang Wei; Xu, Fengrong; Niu Yan; Sun Qi; *Xu Ping

5.535

45

RNA-seq identified a super-long intergenic transcript functioning in adipogenesis.

RNA Biol.

Yi F, Yang F, Liu X, Chen H, Ji T, Jiang L, Wang X, Yang Z, Zhang LH, Ding X, Liang Z, Du Q.

5.436