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2015年代表性论文及影响因子5以上的文章目录

 ●  2015年代表性论文  

2015年药学院在聚焦重大前沿科学问题、引领科学发展方面取得了系统性原创成果,在药学相关领域公认的重要期刊上发表了200余篇高水平学术论文。一系列重要科研成果发表于J. Med. Chem., Eur. J .Med. Chem., J. Nat. Prod., J. Am. Chem. Soc., Angew. Chem. Int. Biomaterials等高水平专业期刊。  

本年度全院共发表论文392篇(SCI收录267篇),会议报告论文127 篇。

1、国内论文140篇,核心期刊收录128篇,SCI收录7篇。

2、国外论文252篇,SCI收录250。其中第一完成单位为我院发表的论文205篇,研究文章204篇,综述4篇。

1)影响因子最高的研究型文章为焦宁教授课题组在JOURNAL OF THE AMERICAN CHEMICAL SOCIETY.杂志上发表的2篇文章Mn-Catalyzed Highly Efficient Aerobic Oxidative Hydroxyazidation of Olefins: A Direct Approach to beta-Azido Alcohols和Rh-Catalyzed Construction of Quinolin-2(1H)-ones via C-H Bond Activation of Simple Anilines with CO and Alkynes,影响因子12.11;王克威课题组还在Nature Communications杂志上发表了1篇文章A Pain-Inducing Centipede Toxin Targets the Heat Activation Machinery of Nociceptor TRPV1,影响因子11.47。

2)国外SCI收录(第一完成单位全部为我院)文章中影响因子11.0~12.1有6篇;7.0~10.0有15篇;4.0~7.0有51篇。

 ●  2015年影响因子5以上的文章目录          


序号

论文题目

杂志名称

 

SCI影响因子

1

Mn-Catalyzed Highly Efficient Aerobic Oxidative Hydroxyazidation of Olefins: A Direct Approach to beta-Azido Alcohols

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Sun, Xiang; Li, Xinyao; Song, Song; Zhu, Yuchao; Liang, Yu-Feng; Jiao, Ning

12.113

2

Rh-Catalyzed Construction of Quinolin-2(1H)-ones via C-H Bond Activation of Simple Anilines with CO and Alkynes

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Li, Xinyao; Li, Xinwei; Jiao, Ning

12.113

3

A Pain-Inducing Centipede Toxin Targets the Heat Activation Machinery of Nociceptor TRPV1

Nature Communications

Shilong Yang, Fan Yang, Ningning We, Jing Hong, Bowen Li, Lei Luo, Mingqiang Rong, Vladimir Yarov-Yarovoy, Jie Zheng, KeWei Wang, Ren Lai

11.47

4

Splitting a Substrate into Three Parts: Gold-Catalyzed Nitrogenation of
Alkynes by C C and C C Bond Cleavages

Angew. Chem. Int. Ed.

Chong Qin, Yijin Su, Tao Shen, Xiaodong Shi, and Ning Jiao

11.261

5

Catalytic Asymmetric Total Synthesis of (-)-Galanthamine and (-)-Lycoramine

Angew. Chem. Int. Ed.

Lei Li, Qiao Yang, Yuan Wang, Yanxing Jia

11.261

6

Protecting-Group-Free Enantioselective Synthesis of (-)-Pallavicinin and (+)-Neopallavicinin

Angew. Chem. Int. Ed.

Bin Huang, Lei Guo, Yanxing Jia

11.261

7

Aerobic Oxidation of Pd-II to Pd-IV by Active Radical Reactants: Direct C-H Nitration and Acylation of Arenes via Oxygenation Process with Molecular Oxygen

ACS CATALYSIS

Liang, Yu-Feng; Li, Xinyao; Wang, Xiaoyang; Yan, Yuepeng; Feng, Peng; Jiao, Ning

9.312

8

Ligand-Promoted Pd-Catalyzed Oxime Ether Directed C-H Hydroxylation of Arenes

ACS CATALYSIS

Liang, Yu-Feng; Wang, Xiaoyang; Yuan, Yizhi; Liang, Yujie; Li, Xinyao; Jiao, Ning

9.312

9

Copper-catalyzed direct transformation of simple alkynes to alkenyl nitriles via aerobic oxidative N-incorporation

CHEMICAL SCIENCE

Huang, Xiaoqiang; Lia, Xinyao; Jiao, Ning

9.211

10

Broaden the versatility of lentiviral vector as a tool in nucleic acid research via genetic code expansion

Nucleic Acids Res

Zheng, Yongxiang; Yu, Fei; Wu, Yiming; Si, Longlong; Xu, Huan; Zhang, Chuanling; Xia, Qing; Xiao, Sulong; Wang, Qi; He, Qiuchen; Chen, Peng; Wang, Jiangyun; Zhang, Li He; Taira, Kazunari; Zhou, Demin

9.112

11

The use of a-conotoxin ImI to actualize the targeted delivery of paclitaxel micelles to a7 nAChR-overexpressing breast cancer

Biomaterials

Dong Mei, Zhiqiang Lin, Jijun Fu, Bing He, Wei Gao, Ling Ma, Wenbing Dai, Hua Zhang,Xueqing Wang, Jiancheng Wang, Xuan Zhang, Wanliang Lu, Demin Zhou, Qiang Zhang

8.557

12

Tumor-specific penetrating peptides-functionalized hyaluronic acid-d-α-tocopheryl succinate based nanoparticles for multi-task delivery to invasive cancers

Biomaterials

De-Sheng Liang, Hai-Tao Su, Yu-Jie Liu, Ai-Ting Wang, Xian-Rong Qi*

8.557

13

Roles of ligand and TPGS of micelles in regulating internalization, penetration and accumulation against sensitive or resistant tumor and therapy for multidrug resistant tumors

Biomaterials

Ai-ting Wang, De-sheng Liang, Yu-jie Liu, Xian-rong Qi*

8.557

14

Efficient bromination of olefins, alkynes, and ketones with dimethyl sulfoxide and hydrobromic acid

GREEN CHEMISTRY

Song, Song; Li, Xinwei; Sun, Xiang; Yuan, Yizhi; Jiao, Ning

8.02

15

From simple organobromides or olefins to highly value-added bromohydrins: a versatile performance of dimethyl sulfoxide

GREEN CHEMISTRY

Song, Song; Huang, Xiaoqiang; Liang, Yu-Feng; Tang, Conghui; Li, Xinwei; Jiao, Ning

8.02

16

Macrophage mediated biomimetic delivery system for the treatment of lung metastasis of breast cancer

Journal of Controlled Release

Jijun Fu , Dan Wang, Dong Mei, Haoran Zhang, Zhaoyang Wang, Bing He, Wenbing Dai, Hua Zhang,Xueqing Wang, Qiang Zhang

7.705

17

A novel localized co-delivery system with lapatinib microparticles and paclitaxel nanoparticles in a peritumorally injectable in situ hydrogel

Journal of Controlled Release

Hongxiang Hu,Zhiqiang LinBing He,Wenbing Dai,Xueqing Wang,Jiancheng Wang , Xuan ZhangHua Zhang*, Qiang Zhang**

7.705

18

The permeability and transport mechanism of graphene quantum dots (GQDs) across the biological barrier

Nanoscale

Xin-yi Wang, Rong Lei, Hong-duang Huang, Na Wanga, Lan Yuan, Ru-yue Xiaoa, Li-dan Baia, Xue Lia, Li-mei Lid and Xiao-da Yang

7.394

19

A comparative study of thermo-sensitive hydrogels with water-insoluble paclitaxel in molecule, nanocrystal and microcrystal dispersions

Nanoscale

Zhiqiang Lin,Dong Mei,Meiwan Chen,Yitao Wang,Xianhui ChenZhaoyang Wang,Bing He,Hua Zhang,Xueqing Wang,Wenbing Dai*Yuxin Yin*and Qiang Zhang*

7.394

20

Effects of PEGylated paclitaxel nanocrystals on breast cancer and its lung metastasis

Nanoscale

Hua Zhang, Hongxiang Hu, Haoran Zhang, Wenbing Dai, Xinglin Wang,Xueqing Wang* and Qiang Zhang*

7.394

21

PSMA-mediated endosome escape-accelerating polymeric micelles for targeted therapy of prostate cancer and the real time tracing of their intracellular trafficking

Nanoscale

Yajie Gao, Yanfang Li, Yushu Li, Lan Yuan, Yanxia Zhou, Jinwen Li, Lei Zhao, Chao Zhang, Xinru Li and Yan Liu

7.394

22

Supramolecular assemblies of novel aminonucleoside phospholipids and their bonding to nucleic acids

Chem. Comm.

Delin Pan, Jing Sun, Hongwei Jin, Yating Li, Liyu Li, Yun Wu, Lihe Zhang, Zhenjun Yang*

6.834

23

Concise Synthesis of the Tricyclic Skeleton of Crotobarin and Crotogoudin via a Gold-catalyzed Cycloisomerization Reaction

Chem. Commun.

Yinliang Guo, Qiang Liu, Yanxing Jia

6.834

24

Photoinduced C–S Bond Cleavage of Thioglycosides and Glycosylation

Organic letters

Run-Ze Mao,Fan Guo, De-Cai Xiong,Qin Li, Jinyou Duan,Xin-Shan Ye

6.364

25

Direct C-H Trifluoromethylation of Glycals by Photoredox Catalysis

Organic letters

Bang Wang,De-Cai Xiong,and Xin-Shan Ye

6.364

26

Cu-Catalyzed Concise Synthesis of Pyridines and 2-(1H)-Pyridones from Acetaldehydes and Simple Nitrogen Donors

ORGANIC LETTERS

Li, Ziyuan; Huang, Xiaoqiang; Chen, Feng; Zhang, Chun; Wang, Xiaoyang; Jiao, Ning

6.364

27

I-2- or NBS-Catalyzed Highly Efficient alpha-Hydroxylation of Ketones with Dimethyl Sulfoxide

ORGANIC LETTERS

Liang, Yu-Feng; Wu, Kai; Song, Song; Li, Xinyao; Huang, Xiaoqiang; Jiao, Ning

6.364

28

Efficient and Practical Oxidative Bromination and Iodination of Arenes and Heteroarenes with DMSO and Hydrogen Halide: A Mild Protocol for Late-Stage Functionalization

ORGANIC LETTERS

Song, Song; Sun, Xiang; Li, Xinwei; Yuan, Yizhi; Jiao, Ning

6.364

29

Metal-Free Nitrogenation of 2-Acetylbiphenyls: Expeditious Synthesis of Phenanthridines

ORGANIC LETTERS

Tang, Conghui; Yuan, Yizhi; Jiao, Ning

6.364

30

Silver-Catalyzed Decarboxylative Azidation of Aliphatic Carboxylic Acids

ORGANIC LETTERS

Zhu, Yuchao; Li, Xinyao; Wang, Xiaoyang; Huang, Xiaoqiang; Shen, Tao; Zhang, Yiqun; Sun, Xiang; Zou, Miancheng; Song, Song; Jiao, Ning

6.364

31

Microbacterins A and B, New Peptaibols from the Deep Sea Actinomycete Microbacterium sediminis sp. nov. YLB-01(T)

Organic Letters

Liu, Dong; Lin, Hong; Proksch, Peter; Tang, Xixiang; Shao, Zhongze; Lin, Wenhan

6.364

32

Asymmetric Total Synthesis of (+)–Dragmacidin D Reveals Unexpected Stereo Complexity

Org. Lett.

Fengying Zhang, Bin Wang, Pritesh Prasad, Robert J. Capon, Yanxing Jia

6.364

33

Exotines A and B, two Heterodimers of isopentenyl-substitutedindole and coumarinderivatives from Murraya exotica.

Org. Lett.

Bing-Yu Liu, Chen Zhang, Ke-Wu Zeng, Jun Li, Xiao-Yu Guo, Ming-Bo Zhao, Peng-FeiTu,and Yong Jiang*.

6.364

34

Traditional Chinese patent medicines for cancer treatment in China: a nationwide medical insurance data analysis

Oncotarget

Wu M, Lu P, Shi L, Li S.

6.359

35

A nanostructure of functional targeting epirubicin liposomes dually modified with aminophenyl glucose and cyclic pentapeptide used for brain glioblastoma treatment.

Oncotarget

Cheng-Xiang Zhang, Wei-Yu Zhao, Lei Liu, Rui-Jun Ju, Li-Min Mu, Yao Zhao, Fan Zeng, Hong-Jun Xie, Yan Yan, Wan-Liang Lu

6.359

36

Application of functional vincristine plus dasatinib liposomes to deletion of vasculogenic mimicry channels in triple-negative breast cancer

Oncotarget

Fan Zeng, Rui-Jun Ju, Lei Liu, Hong-Jun Xie, Li-Min Mu, Yao Zhao, Yan Yan, Ying-Jie Hu, Jia-Shuan Wu, Wan-Liang Lu

6.359

37

Development of next generation of therapeutic IFN-alpha2b via genetic code expansion

Acta Biomaterialia

Bo Zhang, Huan Xu, Jingxian Chen, Yongxiang Zheng, Yiming Wu, Longlong Si, Ling Wu, Chuanling Zhang, Gang Xia, Lihe Zhang, Demin Zhou

6.025

38

pH-responsive polymeric micelles based on poly(2-ethyl-2-oxazoline)-poly(D,L-lactide) for tumor-targeting and controlled delivery of doxorubicin and P-gp inhibitor

Acta Biomaterialia

Yong Zhao, Yanxia Zhou, Dishi Wang, Yajie Gao, Jinwen Li, Shujin Ma, Lei Zhao, Chao Zhang, Yan Liu and Xinru Li

6.025

39

Enhanced antitumor efficacy by cyclic RGDyK-conjugated and paclitaxel-loaded pH-responsive polymeric micelles

Acta Biomaterialia

Yajie Gao, Yanxia Zhou, Lei Zhao, Chao Zhang, Yushu Li, Jinwen Li, Xinru Li and Yan Liu

6.025

40

Targeting and microenvironment responsive lipid nanocarrier for the enhancement of Targeting and Microenvironment-Responsive Lipid Nanocarrier for the Enhancement of Tumor Cell Recognition and Therapeutic Efficiency

Adv. Healthcare Mater.

Wei Gao , Tingting Meng , Nianqiu Shi , Hongmeng Zhuang , Zhenzhen Yang , Xianrong Qi*

5.797

41

Novel mechanisms for superoxide-scavenging activity of human manganese superoxide dismutase determined by the K68 key acetylation site.

Free Radic Biol Med

Lu J, Cheng K, Zhang B, Xu H, Cao Y, Guo F, Feng X, Xia Q*.

5.736

42

Bioorthogonal SERS Nanoprobes for Mulitplex Spectroscopic Detection and Tumor Cell Targeting and Tissue Imaging

Chem. Eur. J

Junzhou Wu, Duanwei Liang, Qingqing Jin, Jie Liu, Meiling Zheng Xuanming Duan, and Xinjing Tang

5.731

43

Cationic Cobalt(III)-Catalyzed Aryl and Alkenyl C-H Amidation: A Mild Protocol for the Modification of Purine Derivatives.

Chemistry (Weinheim an der Bergstrasse, Germany)

Liang, Yujie; Liang, Yu-Feng; Tang, Conghui; Yuan, Yizhi; Jiao, Ning

5.731

44

Biocatalysis of cycloastragenol by Syncephalastrum racemosum and Alternaria alternata to discover anti-aging derivatives.

Adv. Synth. Catal.

Lin-min Feng, Shuai Ji, Xue Qiao, Zi-wei Li, Xiong-hao Lin, Min Ye*.

5.663

45

Visualizing Fluoride ion in Mitochondria and Lysosome of Living Cells and in Living Mice with Positively Charged Ratiometric Probes

Anal. Chem

Zhisheng Wu, Xinjing Tang

5.636

46

Therapeutic potential of targeted multifunctional nanocomplex co-delivery of siRNA and low-dose doxorubicin in breast cancer

Cancer Letters

Dawen Dong,Wei Gao, Yujie Liu, Xian-Rong Qi*

5.621

47

Systemic Administration of siRNA via cRGD-containing Peptide

Scientific Reports

Huang Y, Wang X, Huang W, Cheng Q, Zheng S, Guo S, Cao H, Liang XJ, Du Q, Liang Z

5.597

48

Photouncaged Sequence-specific Interstrand DNA Cross-Linking with Photolabile 4-oxo-enalmodified Oligonucleotides

Sci. Rep.

Jingjing Sun, Xinjing Tang

5.578

49

Natural small molecule FMHM
inhibits lipopolysaccharideinduced
inflammatory response by
promoting TRAF6 degradation via
K48-linked polyubiquitination

Scientific Reports

Ke-Wu Zeng1, Li-Xi Liao1, Hai-Ning Lv1, Fang-Jiao Song2, Qian Yu2, Xin Dong1, Jun Li3,
Yong Jiang1 & Peng-Fei Tu1

5.578

50

Neuroprotective Effects of a standardized flavonoid extract of safflower against Neurotoxin-Induced Cellular and Animal Models of Parkinson's Disease

Scientific Reports

Rutong Ren, Chunyan Shi, Jing Cao, Yi Sun, Xin Zhao, Chen Wang, Yongfei Guo, Hui Lei, Hanjie Jiang, Nuramatjan Ablata, , Jiamin Xu, Wan Li, Yingcong Ma, Xianrong Qi, Min Ye, Xiaoping Pu*, Hongbin Han, *

5.578

51

Cyclic Adenosine 5 '-Diphosphoribose (cADPR) Mimics Used as Molecular Probes in Cell Signaling

CHEMICAL RECORD

Zhang, Liangren; Yue, Jianbo; Zhang, Li-He

5.492

52

Discovery of Pentacyclic Triterpenoids as Potential Entry Inhibitors of Influenza Viruses.

J. Med. Chem.

Maorong Yu, Longlong Si, Yufei Wang, Yiming Wu, Fei Yu, Pingxuan Jiao, Yongying Shi, Han Wang, Sulong Xiao, Ge Fu, Ke Tian, Yitao Wang, Zhihong Guo, Xinshan Ye, Lihe Zhang

5.48

53

Highly Substituted CyclopentaneCMP Conjugates as Potent Sialyltransferase Inhibitors

Journal of Medicinal Chemistry

Wenming Li,Youhong Niu, De-Cai Xiong,Xiaoping Cao,nd Xin-Shan Ye

5.447

54

A Combination of Targeted Sunitinib Liposomes and Targeted Vinorelbine Liposomes for Treating Invasive Breast Cancer

Journal of Biomedical Nanotechnology

Ji-Feng Shi, Meng-Ge Sun, Xiu-Ying Li, Yao Zhao, Rui-Jun Ju, Li-Min Mu, Yan Yan, Xue-Tao Li, Fan Zeng, and Wan-Liang Lu

5.338

55

Structure-guided creation of AcAP5-derived and platelet targeted factor Xa inhibitors

Biochem Pharmacol

Zhu Y, Lin Y, Liu A, Shui M, Li R, Liu X, Hu W, Wang Y

5.009

56

Dopamine enhances the response of sunitinib in the treatment of drug-resistant breast cancer: involvement of eradicating cancer stem-like cells

Biochemical Pharmacology

Wang, Siyuan; Mou, Zhenzhen; Ma, Yuanheng; Li, Jian; Li, Jingyun; Ji, Xiwei; Wu, Kehua; Li, Liang; Lu, Wei; Zhou, Tianyan*

5.009